[DBS seminar] Urban Čoko, "Particle-based simulations of ultrasound in a GHz to MHz frequency range"
Seminar room of physics (106)
IJS
Ultrasound is increasingly used in biomedical applications such as drug and gene delivery, where acoustic waves interact with microbubbles, cells, and tissues. While particle-based simulations are widely used in biophysics to model such structures, their use for ultrasound propagation remains largely restricted to nanoscopic scales. In this talk, I will present a novel particle-based method for simulating ultrasound propagation in weakly compressible fluids on micrometer scales, spanning frequencies from GHz to medically relevant MHz. The method is fully compatible with existing particle-based models of biological structures. Building on this method, I will present a virtual ultrasound machine that models arbitrary particle-based structures immersed in a fluid between two ultrasound transducers. As a demonstration, the machine is used to simulate microbubble motion driven by acoustic radiation forces, a phenomenon known as "acoustophoresis".

Theoretical Biophysics and Soft Matter Group